Haemophilia: A rare blood-clotting disorder that runs in families



Skin that bruises easily, unexplained and prolonged nosebleeds, and excessive bleeding from an injury are some symptoms of haemophilia, a rare disorder associated with impaired blood clotting. Bleeding is prolonged because of a deficiency in certain proteins known as clotting factors.

There is currently no cure for haemophilia, which tends to run in families and mostly affects males, though recent clinical trials have shown promising results.

Patients can suffer external bleeding – e.g. from cuts and wounds – and internal bleeding – e.g. in the brain, abdomen and muscles/joints. In patients with severe haemophilia, symptoms typically show up in early childhood, while in mild to moderate cases, symptoms may appear in late childhood, adolescence or even in adulthood, often after an injury, or dental/surgical procedure.

While, you are usually born with haemophilia, in rare cases, you can develop it as an adult when your immune system attacks the clotting factors in your blood. This is associated with pregnancy, autoimmune conditions, cancer and multiple sclerosis.
What causes haemophilia?

Haemophilia is typically caused by a mutation on the X chromosome. If the X chromosome of a male carries the haemophilia gene mutation, he will develop the disorder but a female who has the haemophilia gene on one of her two X chromosomes, is likely to be a carrier and has a 50 per cent chance of passing the haemophilia gene to her children.

The two major types of haemophilia are haemophilia A and haemophilia B, caused by a deficiency in clotting factors 8 and 9 respectively.
How is haemophilia diagnosed and treated?

Haemophilia is diagnosed with the help of a blood test for clotting factor deficiency. Treatment is based on the severity of your condition and involves factor replacement therapy via injections.

For severe haemophilia, injections are administered regularly, while in mild to moderate cases, injections are given only during episodes of prolonged bleeding.

Internal bleeding, particularly in the brain, can be life-threatening and requires emergency treatment in a hospital.

If you have haemophilia, you are advised to get immunised against hepatitis A and B.

Tips for living with haemophilia


1. Act quickly and control any bleeding with first aid.Strengthen your joints and muscles and lower your risk of internal bleeding with swimming and non-contact sports such as badminton and table tennis.
2. Avoid contact sports, e.g. rugby and football, which can cause injury to the abdomen and the head.
3. Maintain good oral hygiene to avoid gum disease.
4. Avoid taking aspirin and ibuprofen which can worsen bleeding.

Small children jumping on bosu balls on training class.

There are business opportunities in a variety of areas in the children's services market, including:

    Quality preschool education, including environmentally-focused offerings such as outdoor preschools

If you enjoy working with children and have instructional training and/or experience, why not turn it into a business?

05. Home Renovations

Contractor

If construction is in your blood and you think you would enjoy making clients' home renovation dreams come true why not turn it into a business?

Ask almost anyone who is needs repairs or renovations done on their home (or business) - remodeling contractors are hard to find and the good ones are always busy. Home renovation is one business that always seems to do well, even in uncertain economic times.

 

Statistics show that the average home owner in the U.S. spends approximately $3000 per year on home improvements - generating a lot of business for carpenters, painters, drywallers, roofers, tilers, and other tradespeople.

 

The home renovations business is ideally suited to self-employed individuals for a number of reasons:

     Most renovations are performed on a contract basis

    Startup capital investment for tools and machinery is typically much less than required for new construction

    Business premises are not required as the work is performed at the customer location, making remodeling a perfect home-based businesses

Remodeling contractors provide services in a number of different ways:

     As individuals, where the contractor performs most or all of the work themselves

    As general contractors, who hire and supervise employees or subcontractor who perform the work

As specialists in a particular area, such as bathroom or kitchen renovations, or niches such as restoring historic structures, improving energy efficiency, or solar installations

 

To be a successful renovation contractor you should have:

    Extensive experience in building construction, with hands-on expertise in at least one of the trades and knowledge of the others

    Good contacts within the industry, so if needed you can call in sub-contractors to get specialty work performed in a timely fashion (such as architects, structural engineers, licensed electricians, plumbers, tilers, etc.)

    Up-to-date knowledge of the local building codes and safety regulations

    Licensing and certification if required in your jurisdiction. In the U.S., the National Association of the Remodeling Industry offers various levels of certification for remodellers.

    Good organizational skills

06. Bike Sales, Service and Rentals

Bicycles for sale in shop

Given the health and environmental benefits, it's no wonder that bicycling has become the second most popular outdoor activity in America by frequency of participation. According to peopleforbikes:

    U.S. bike commuting has grown 47 percent nationwide and 73 percent in the largest cities over a 10-year period. North American cities are trying hard to increase the number of people using bikes rather than cars to commute to work.

    Americans spend $81 billion on biking annually, generating 770,000 jobs.

Anything that’s healthy, popular, good for the environment and heavily promoted by government is a pretty good business bet. In addition to pedal-only powered bikes, E-bikes have become very popular. E-bikes can be pedaled without electric power or use electric power to assist, and sales are expected to hit close to 50 million units by 2018. Regular pedal bikes can be converted to E-bikes with a kit that allows replacement of the front or back wheel hub with one containing a small electric motor and adding a battery and cabling.

If cycling is your passion and you want to become an entrepreneur, this may be the perfect business opportunity for you.

07. Senior Care Services

Carer holding hand of senior woman

Senior care services continue to rank as one of the best business opportunities. Demographics play a big role. The first baby boomers hit age 65 in 2011. The entire baby boomer generation will have will have reached age 65 by 2030. Seniors will make up 1/4 of the entire U.S. population. Unfortunately, although they are expected to live longer lives than previous generations, it's also expected that they'll spend more years in sickness, according to a report on senior’s health by the not-for-profit United Health Foundation.

Fortunately, baby boomers are a wealthy demographic compared to previous generations. For the most part, they can afford to pay for the services necessary to maintain their lifestyles. This includes continuing to live at home in their own communities. According to research by the American Association of Retired Persons (AARP), nearly 90 percent of seniors have this goal.

Many affluent seniors suffer from various health and/or mobility issues and are increasingly uncomfortable or unable to drive their own vehicles. They may find it difficult or impossible to take care of household chores such as landscaping, cleaning, cooking or caring for their pets. Others travel extensively and require house sitting or pet sitting and property maintenance services. All in all, a wealth of opportunities exist for entrepreneurs who wish to take advantage of the senior care trend. If you're not interesting in starting your own business from scratch, various senior care franchise opportunities are available.

08. Body Decoration Services (Piercings and Tattoos)

Tattoo

According to statistics, the tattoo industry generated $3 billion in revenue in 2014 and continues to grow rapidly:

    40 percent of American households have at least one member with a tattoo, up from 21 percent in 1999

    22 percent of young millennials have at least one tattoo

    30 percent of people aged 25-39 have tattoos and 40 percent of adults aged 30-39

    Tattoos are also popular with middle-aged adults ​— 30 percent of those aged 40-49 have at least one

Most tattoo artists learn the trade via an apprenticeship alongside a professional (typically three years or more). For health and safety reasons, some jurisdictions require classroom experience.

If you have artistic and creative skills, becoming a tattoo artist can be an excellent business opportunity.

09. Counseling and Therapy

The mental health field is another profession that is experiencing increased demand for services. The BLS expects the need for marriage and family therapists to grow 41 percent by 2020.

The nature of mental health counseling makes it suitable for private practice. Many professionals in the field make the occupational choice to start their own counseling businesses. This typically requires extensive schooling, however, and often post-graduate degree.

10. Financial Advisor/Planner

Businessman meeting with clients

Financial advisers/planners are expected to be in high demand with a projected growth rate of 30 percent through 2026, according to the U.S. Bureau of Labor Statistics. Studies in Canada indicate that only 20 percent of Canadians have confidence in their math and money skills as they relate to planning for a secure financial future, according to a 2011 survey by Ipsos Reid for ABC Life Literacy Canada.

  Becoming a financial adviser/planner normally requires a bachelor's degree and additional training in securities management, leading to licensing/certification. But this is another business that is riding the demographic wave. A huge pool of baby boomers are headed for retirement, and they need and want help with their finances. Financial advising and planning is an ideal business opportunity.


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